Page 20 - Vol.38-No.1

DAIRY FARMING

ANPARIO AWARDED UK PATENT FOR OREGO-

STIM, THE COMPOSITION OF WHICH REDUCES

ANTIMICROBIAL RESISTANCE IN CALVES

Anpario have successfully been Antimicrobial resistance is one of the same ration of untreated waste milk
granted a UK patent for their leading the greatest threats globally to human and concentrates until weaning at 8
phytogenic product Orego-Stim. The health and has been predicted to be weeks of age.
composition of which is effective in re- responsible for 10 million deaths a year In the faeces of calves fed waste milk
ducing antimicrobial resistance*. by 2050 if not acted upon. with no Orego-Stim, 44.1% of E. coli
The patent grant follows a combined University researchers Dr Partha Ray present were resistant to the cephalo-
and successful research programme and Dr Caroline Rymer, undertook the sporin antibiotic (cefquinome). How-
with the University of Reading. The trial to determine the effect of supple- ever, in calves fed waste milk supple-
research demonstrated that the pro- menting Orego-Stim Liquid, a source mented with Orego-Stim Liquid until
portion of E. coli bacteria resistant to of 100% natural oregano essential oil, day ten, this was significantly reduced,
a fourth-generation cephalosporin an- in waste milk fed to dairy calves, on with only 12.6% of total E. coli being
tibiotic, can be significantly reduced the population of antimicrobial resistant resistant to cefquinome.
by adding Orego-Stim Liquid to calf bacteria in their faeces. This resistance Dr Partha Ray commented “Orega-
diets, according to research undertaken can occur when calves are fed waste no essential oil supplementation
at the University of Reading in the UK. milk or colostrum containing antibiotic not only reduced the abundance of
residues. cefquinome-resistant E. coli but also
Waste milk occurs on farms when delayed the emergence of resistance
cows have been treated for a disease, to cefquinome”.
such as mastitis, with antibiotics. The David Wilde, Anpario’s Global Inno-
milk from these cows cannot be sold vation Manager and Ruminant Special-
for human consumption and, as it con- ist summarised the importance of the
tains valuable nutrients, is often fed to research. “Waste milk is a valuable re-
pre-weaned calves. source on all dairy farms and disposing
In the trial, two-day old Holstein male of it in slurry lagoons only transfers the
calves were offered either waste milk AMR issue elsewhere. This important
with Orego-Stim Liquid added for the work shows that it may be possible to
first ten days or a control diet of the support gut and animal health when
same waste milk source without the using natural products, such as Ore-
addition of Orego-Stim Liquid. After go-Stim, and allow the continued use
the initial ten days, all calves were fed of this vital calf feed.”
Circle 19 on enquiry card
CANADIAN RESEARCHERS WORKING ON NEW TESTING

METHOD FOR CATTLE-ADAPTED SALMONELLA BACTERIA

A research team at the Western Col- not to get sick from it. But calves do, as the “Typhoid Marys” of the bovine
lege of Veterinary Medicine (WCVM) and they get sepsis (systemic infection) world. The bacteria are difficult to
is developing a more cost-effective and basically get multi-organ failure culture from feces, which is how it is
method to detect a type of salmonella and may be euthanized or die,” says spread among the carriers’ herd mates.
bacteria that’s difficult to diagnose and Dr. Chris Luby, an associate professor “They [the carriers] show no clinical
even more difficult to eradicate from in the WCVM’s Department of Large signs, yet [they] are spreading it around
dairy cattle herds. Animal Clinical Sciences and the pro- the dairy farm and it’s really hard to
a serotype or strain of the bacteri- ject’s lead researcher. identify those,” says Luby.
um Salmonella enterica, is an emerging “It [S. Dublin] does compromise ani- Right now, the only reliable way to
disease in Canada and a growing con- mal welfare, and it is a potential threat ensure that S. Dublin infection is eradi-
cern for the country’s dairy farmers. In to human health.” cated is to take regular blood tests from
Saskatchewan, each diagnosis of the S. Dublin can occur in humans, al- every animal in a dairy herd — a costly
bacterial disease must be notified to though it’s not common. When people option.
the provincial government as a means get this type of salmonella, they are The idea for the WCVM study came
of monitoring. susceptible to sepsis instead of suffer- about after there was a S. Dublin out-
“Salmonella Dublin is a cattle-adapt- ing the typical symptom of diarrhea. break at the University of Saskatche-
ed strain, which means adult cows tend Luby describes S. Dublin carriers wan’s (USask) Rayner Dairy Research

18 Vol. 38 No. 1